The Biochemistry of Mucopolysaccharides of Connective Tissue

نویسنده

  • Lewis N. Lukens
چکیده

suitably curved surfaces. 3) Point projection whereby electrons are focussed to a fine spot on a thin target which then becomes a source of X-rays to project a magnified image of an object by rectilinear propagation, and 4) scanning methods whereby a fine electron beam probe is made to scan point-by-point the surface of the object itself or a thin metal target in close contact with the object. In the former instance the picture appears in terms of variations in X-ray emission and in the latter instance the object is portrayed in terms of absorption characteristics. The first three of these main methods are of general application and at present have attained a resolving power of from 1000 to 2000 A, or approximately the limit of the light microscope. There are possibilities, in theory, of improvement down to about 100 to 200 A but owing to certain grave technical difficulties the prospects of reaching this degree of performance in the near future do not appear very good. This leaves the prospects far short of the resolving power of the electron microscope which is about 5 A. The topics discussed in the book fall into three main categories: 1) description and analysis of the instrumentation along with the physics of image formation, including such considerations as the interaction of X-rays with the object; 2) techniques in the production of X-rays and in the preparation and examination of materials; and 3) examples of applications of X-ray microscopy in biology and medicine, metallurgy, geology, industry and other fields, with 32 plates showing pictures of apparatus and magnified X-ray images of specimens. There is also a chapter on the analysis of very small crystals by X-ray diffraction (microdiffraction) and one on recent refinements in special methods. The bibliography is extensive and an appendix contains tables of X-ray absorption data. This book should prove to be a useful and handy reference for all who are concerned with the microstructure of materials. CECIL E. HALL

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عنوان ژورنال:
  • The Yale Journal of Biology and Medicine

دوره 34  شماره 

صفحات  -

تاریخ انتشار 1962